Projects

Burnet Institute

Evaluation and prediction of the effect of combinations of antimalarial drugs

As a consequence of emergence of resistant parasites to current drug regimes, the development and use of combinations of antimalarial…

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An external quality assurance program for PCR assays to quantify parasitaemia across laboratories in the Asia-Pacific region

PCR-based techniques for the diagnosis and quantification of human malaria infections are more sensitive and precise than standard microscopy methodology….

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Development of Novel Antimalarial Drugs that Target Proteostasis

Because current antimalarial control is highly dependent on artemisinin combination therapies (ACTs), it is extremely concerning that decreased sensitivity has…

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Epidemiological modelling for malaria elimination

Mathematical models of transmission provide a framework in which to evaluate the likely impact of novel diagnostic, surveillance and treatment…

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Molecular surveillance of malaria parasites to inform on local intervention strategies

The successful elimination of malaria will require diligent surveillance with innovative new tools to help control programs to monitor parasite…

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Within-host malaria modelling to improve the treatment of malaria

Approximately 200 million clinical cases of malaria are treated globally each year. Artemisinin derivatives are the first line treatment for…

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Access and adherence to malaria interventions

Elimination will depend upon improved access to early diagnosis and treatment, high quality care, and adherence. ACREME investigators are involved…

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Impact of declining transmission on malaria treatment outcomes, immunity and risk of rebound

As malaria transmission falls, it is critical to understand how changing immunity affects risk of infection, clinical disease and, most…

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Geographical information systems and spatial decision support systems.

Malaria elimination results in heterogeneous pockets of transmission that need to be identified and then targeted with specific interventions that…

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Pregnant women and malaria surveillance

To know whether malaria is being transmitted in a community, it is necessary to test community members for malaria parasites…

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