Publications

Mayeta Clark 2015

Monitoring Plasmodium falciparum and Plasmodium vivax using microsatellite markers indicates limited changes in population structure after substantial transmission decline in Papua New Guinea

September 28, 2020

Monitoring the genetic structure of pathogen populations may be an economical and sensitive approach to quantify the impact of control…

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Evaluation of the effectiveness of topical repellent distributed by village health volunteer networks against Plasmodium spp. infection in Myanmar: A stepped-wedge cluster randomised trial

August 20, 2020

Background The World Health Organization has yet to endorse deployment of topical repellents for malaria prevention as part of public…

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Identifying and combating the impacts of COVID-19 on malaria

July 30, 2020

Background The COVID-19 pandemic has resulted in millions of infections, hundreds of thousands of deaths and major societal disruption due…

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Innate immune responses to malaria-infected erythrocytes in pregnant women: Effects of gravidity, malaria infection, and geographic location

July 29, 2020

Background Malaria in pregnancy causes maternal, fetal and neonatal morbidity and mortality, and maternal innate immune responses are implicated in…

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Implementing parasite genotyping into national surveillance frameworks: feedback from control programmes and researchers in the Asia–Pacific region

July 27, 2020

The Asia–Pacific region faces formidable challenges in achieving malaria elimination by the proposed target in 2030. Molecular surveillance of Plasmodium parasites can…

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Plasma cell-free DNA predicts pediatric cerebral malaria severity

June 18, 2020

Background Prediction of adverse outcomes in cerebral malaria (CM) is difficult. We hypothesized that cell-free DNA (cfDNA) levels would facilitate…

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Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection

June 18, 2020

Objectives Malaria, caused by Plasmodium infection, remains a major global health problem. Monocytes are integral to the immune response, yet their transcriptional…

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Population Pharmacokinetics and Pharmacodynamics of Chloroquine in a Plasmodium Vivax Volunteer Infection Study

May 16, 2020

Chloroquine has been used for the treatment of malaria for more than 70 years; however, chloroquine pharmacokinetic (PK) and pharmacodynamic…

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Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis

May 14, 2020

Background The radical cure of Plasmodium vivax and P. ovale requires treatment with primaquine or tafenoquine to clear dormant liver stages. Either drug can induce…

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Cost-Effectiveness Analysis of Sex-Stratified Plasmodium vivax Treatment Strategies Using Available G6PD Diagnostics to Accelerate Access to Radical Cure

May 4, 2020

Tafenoquine has been licensed for the single-dose radical cure of Plasmodium vivax in adults; however, it is only recommended in patients with…

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