Mayeta Clark 2015

Identifying and combating the impacts of COVID-19 on malaria

July 30, 2020

Background The COVID-19 pandemic has resulted in millions of infections, hundreds of thousands of deaths and major societal disruption due…

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Implementing parasite genotyping into national surveillance frameworks: feedback from control programmes and researchers in the Asia–Pacific region

July 27, 2020

The Asia–Pacific region faces formidable challenges in achieving malaria elimination by the proposed target in 2030. Molecular surveillance of Plasmodium parasites can…

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Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection

June 18, 2020

Objectives Malaria, caused by Plasmodium infection, remains a major global health problem. Monocytes are integral to the immune response, yet their transcriptional…

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Population Pharmacokinetics and Pharmacodynamics of Chloroquine in a Plasmodium Vivax Volunteer Infection Study

May 16, 2020

Chloroquine has been used for the treatment of malaria for more than 70 years; however, chloroquine pharmacokinetic (PK) and pharmacodynamic…

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Quantification of glucose-6-phosphate dehydrogenase activity by spectrophotometry: A systematic review and meta-analysis

May 14, 2020

Background The radical cure of Plasmodium vivax and P. ovale requires treatment with primaquine or tafenoquine to clear dormant liver stages. Either drug can induce…

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Cost-Effectiveness Analysis of Sex-Stratified Plasmodium vivax Treatment Strategies Using Available G6PD Diagnostics to Accelerate Access to Radical Cure

May 4, 2020

Tafenoquine has been licensed for the single-dose radical cure of Plasmodium vivax in adults; however, it is only recommended in patients with…

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Multifunctional Antibodies Are Induced by the RTS,S Malaria Vaccine and Associated With Protection in a Phase 1/2a Trial

March 31, 2020

This study evaluated functional antibody responses in clinical trials of RTS,S and demonstrated for the first time that vaccination with RTS,S induces antibodies that function to recruit complement and activate specialised immune cells against malaria.

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The risk of morbidity and mortality following recurrent malaria in Papua, Indonesia: a retrospective cohort study

February 20, 2020

Background An acute episode of malaria can be followed by multiple recurrent episodes either due to re-infection, recrudescence of a…

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Malaria-related hospitalization during childhood in Papua, Indonesia: A retrospective cohort study

January 29, 2020

Background: In endemic regions, the age distribution of malaria varies according to the infecting Plasmodium species. We aimed to delineate the…

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